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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eaa840273f6dae2e1018f5f7cf1e41e0197d4463754be6a884298a21c20eb3c' 
  AND token = 'VlwVzjJwdVtbt7JcOAovKZuEQoJ+4VVE6pApb/btlFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}