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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd721c5f42d529931d1ea8aed147c5126334db62f4c08175131fe18ab1d26456' 
  AND token = '28tkhSINzb2FJEGt6+ipGEMSXN4rzsDa/7XupB669DA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}