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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74f0d3448559f965ce263df544f2fa4378a19badffbc7dc0ec897f1bb164c2a4' 
  AND token = 'PzNB3T5o0z1m7sHd5CWtMLpY+Df82GIqZ1Ek9UqJlyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}