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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce423c20ba74efc0d28f521f642ac41dd0ffb2cbac0abe0d6b15e1e74cde3370' 
  AND token = 's6eHAv9WOe09B9ERm48TtsltmcUHEgIOUP2tn8V86Dk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}