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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a0323650f56e2ad6ae03a17bb7f7a15a46590457116f14dba0f56e35b225db1' 
  AND token = 'wmGw7bJ3TJcIG4dNW/N9soudTRloAmWmmGyYrI4Zprk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}