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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34bb7df99113c3dd666636cf310e787da25ab7301a6062e43c4f4a7f9b7eba5d' 
  AND token = '6ELFwdBg9nrp3RP86ZYTfFZ1y1ztFMbItZiB5UOHtpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}