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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee525b186af85c18d34b9d5bf5e02298873be5bc0c5ffcf2d52c9cbdd1de5ee8' 
  AND token = 'TVTu0VLn4q5/TuOyBPGmdy4DJok/0LsRO4SA/sH1NZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}