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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e05e84bfa67957c42e08aae13c2dfd0d866b0867d82b4a4d6aea3443fae3dc1' 
  AND token = 'i6FNlcd6awyy1yjRlRGWS+XZJAn9SkbghrqlPE+RmDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}