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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbf01f62431c737766ef5287dcee518ed799de48625cb921c6af88ac1a50b635' 
  AND token = 'v36D4xbo36svwknZcvySRHVxh+rNSVKgxhCEyO/DDWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}