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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '525399351689762e24df805c9972a626c5402e77c046628e44f59b377ad23d7b' 
  AND token = 'Hw3KFcEbmBbyt8/UN4CAyQA3T/pUNrtM/gAy4moBSpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}