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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '002c203c38709992fc456cec3b0206973cb8cdffda96553e62cb39ebae47e266' 
  AND token = '0ZosLpO4iQPwbD4aUATyD2WQxbK0M06xNdahI1CewrU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}