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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80972f89ff6d2493530c9599ce7b163a015f9cf717af8e83dc8e63d4fa11f3e0' 
  AND token = 'jqPrnquqbmnLpZeZk2uU9TK3P0zZTd2th66WokV1p50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}