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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28c1b79eee6bf7b203ff6b138567bb672bce0dff538d14f055cb558f6f15059a' 
  AND token = 'UQ0m++1gE4j2TySgSM2hIxBgreva4vRFgouWeYs8DEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}