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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77a37a19db1dc8865467153746b14bca5ccc9558f0f2c5491aa71efb69b9cb21' 
  AND token = 'jE4ZO6y5l4a/kpIDMpZqehIgSz6y5AxlPLgASPksJuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}