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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c543771da567146a7fb94b327a1c8b49fcc65fbe6e77d6ac6b23a3c509803db' 
  AND token = 'Y/3QQBFgIh7/ctefxE4eMb7YXZaDG0OZXZH9XPcjyF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}