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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f358c0fa583610ff4e3007a3532af1b53c2e27883b29d6afcdddbfaaebf6851' 
  AND token = 'OK4wxf4d8UuuG9Z/yhTegdcRLjybIP4y5KJ9e6X4NuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}