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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '450af052a814534efb7e0ef3ee33506ab2db7e8c2ab7700b808ef2ecb5d0ded2' 
  AND token = 'oZYj/nx7593QpqBpStTkCu++2MYyNv0mJJbVvj1XHA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}