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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2e83ce49d4e92fc0c2b190d3a2be740adff38f2e0ecf137648f9bee87e57d13' 
  AND token = 'P6UBjNBh2TqJ+gqFE9CLbf4X9DvoZINC3cbEZh2qbAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}