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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8868b285d58c405f0caa38420d2b8a31afb92b427afb823c03ae8cbecffb8d3f' 
  AND token = 'yyaSg44S7MqHF+A3RujdMvdC1Idia+1N9Z02jfJaZjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}