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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb64c72dfb0fb345e93a46c40e9589477ef434c209de7cdb21d801a705dd8917' 
  AND token = 'Qbb7/U8iz5RPIosFjLQC+enA+YDoqQwyqfN/RA4DGt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}