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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '808775b0d0b0b766b02141e75e8df74ae3291767658f76e9f66022a9999f9520' 
  AND token = 'VxhswZmzfRhSoo4kJcgFpVp/OUeB4ORDahcUbX2/AT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}