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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b222f7c47197db0f37044f0d240bf005d7c700d4becd6cbf034c3d83bb0140f' 
  AND token = 'Mc4fGk3Bdd+zJHoqFE3yg/tADUQbbx5Qz3zuBPc5FO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}