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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f0622ffd86633d9828d6341005edcac5092a9e6bff621ea841f95d8647bba1d' 
  AND token = 'Zbbepoba+ePcsX0p8Ntfj6VB7NTeMUuQSKEyfu3AtXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}