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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3504a377e06aa513c9dc28a5907565e132cd75ce9b21923946310c0e53a59c94' 
  AND token = 'xouHW9fMbMkQ5Pam5EPwL029rYAJe2dT4jtZYJBOT7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}