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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7efe2d53d50b855aebaff6bf801db11d320f81e78c95101b6d075995102b7c6f' 
  AND token = 'BLY2/0cyqN4nwBoPTf7JjHIP9IELVo9nSV9lCrwyzEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}