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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '693ef17eac2880b9a5d49e81bad889dda8a18636ba626623073fb5d6afd18cee' 
  AND token = 'mDqIGviu35aPD4Td1+FFqggc6GyBzUoHh9zT7cO0MY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}