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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d11b37465bb3f0819e2d1249214cb9cc8f61d7758983007977556da6cda17f0' 
  AND token = 'MV5xKFL2Kk7B/XQcWB63b78tQai4p4b1UWLEgTEZwOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}