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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad454a10c90559ebecc54c3e4db7eaabc250b66147d51f343d1deaf99be342e4' 
  AND token = 'IM5hRz5XS6BzSDpdyVwnT8Xme+l1qMZI1uUHrFvwRDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}