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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdf6558f339c71645f729f7f3a3f85b223d1c0e35e95a667d2bded80b315b334' 
  AND token = 'NM06QlGFqfvN86xRIyRFyB97P7py1Q2e2Uk3pr3BD1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}