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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cd3be9eafc727e920cbf8ea3ad30bdbba3bfb730e086264368109527d0b72f5' 
  AND token = 'uDzGF/9S/Vk/HI3/IofV1njTyx4+NnxIvB1aI8xh+nk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00070

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}