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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9111b6de46f891de4d2e87bfb73624eb2db4773a8c87993183314f26f28e63f' 
  AND token = 'N9mR2iK36i2mrAzHR+sgqIY/Wsky59mwQC6XXbp9/zA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}