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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39c2083bdcb5ea7aa2296cc75c641eaf1785c338498219bda5ec414307997487' 
  AND token = '35MS9bodmLRBOBT9SO2wkgM/47XQPBB4S1mXBN/e9r4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}