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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40c65a236dc9b566bb9b3ed231bc729b5286e0e70cb2484128593943e9158859' 
  AND token = 'fddbmxHTaT+ObL0fssvb4xRvBfzFtWH/OFi7fcJOjpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}