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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec7780d74c6ee56471749cc7a9d2844eb94f8aa386d9b9c6fd2a2b52919dea2a' 
  AND token = '1jHqWjDfGM2SgxR0y6OtSZgyLO9DxMAgLB7WhFgrokg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}