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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cef122eb09d59aff2ffc8f278e101ec61c242b0ce44c50ca06223aef01995051' 
  AND token = 'vCiszB7XAOSbXLExEY9oDbaAGmXY+M/uIHemhGe7/pk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}