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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '629483f4876e4d3391d476caf24444c8d6988b3aee6adc6d4bd3648317c20180' 
  AND token = '+XX9vD/m3klo4ebF4R8sjlSvFnuxFIhTCQ+S0p1Cv8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}