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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1e1e8cbce4bb7006a0f232d00911c5982dec7700d210c5be57da5a5fc481e71' 
  AND token = 'PGi4JueoTW9RoAszLFkPLk1HNiLeRXOIuPMOqTb4MJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}