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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf7d4bd531f0fa1e112cb9124e0c18e8ca7ef47e1a678c429e3ebc4fcf60ba49' 
  AND token = 'pfUUOqQzYWlG9mTRpyLzG8SG+jyx0TzmwO9GbAcPIhY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}