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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a883d0b96305e47149a71c6b82187fe6a1c0d7619fe3b108a9ecc57d649fe606' 
  AND token = 'PL9YaPy5Gc6fYTv+cvXJTXrtrOylarhjKWk0cEbBkH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}