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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dbf31e631f1503d43aedf5129ec55d6ae1859d0e342d30d7056b32ac4a2bfb2' 
  AND token = '9CagcvpWJYK5oEYO5I/rXQq8hurzkKOrAOopKLTgMTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}