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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '174714e5c225b84499f49c6b6f931c1d371aaab8d65190ff8a20248863e331f4' 
  AND token = '25aYxCrpzH28aC9weaisem2amQA56cTsG6kFv2Ns+EU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}