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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f609ec0ee6e7239b760a2569d3f15fb64e504ec533d40a0ec1d9f6463fb85b6c' 
  AND token = 'lGITzk+c6o8TxMQMgyq52jGHGi6nJcOazKBBycuYVzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}