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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c65884244360ea04d00005322ffd89c9da81251958078f24e842086e41bc5d34' 
  AND token = 'lNPCVwlSxJW4meNHahI6CBiZj9rjNH/qTJD2mwBUNYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}