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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c41799efd7a48c07eb6746fcc2b7d297745f35ebdfc9396e973d50b0f4d09195' 
  AND token = 'qQnPRwXb6T45EyANkXiU/vOfod8YeRQ2AWZdk5vBpUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}