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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65af2e19be558531d68ee1e65d779bb26c270422053464731891707bd80ee175' 
  AND token = 'E5AEhzQcQe8y3rQ/ArYYWgiqmq5YTqdpqnLAk8ct38Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}