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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13514b799e0fb6bae1d8462924ae0ba5545ec13cde53b08249c725964f3b1cd1' 
  AND token = 'xODsWN1m0utfRBEGrXT9i+BxvnYZHsaQOhMFOaN5TC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}