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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1db32a08c3b42a0378f58c5acf50c9c67adeb86bbfeb1219d352ebbde0865d9' 
  AND token = '+sX8BqHaonrMR0zefxBml8yZE9dqh44ZeQL/D+lNsPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}