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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2037308db50f1809cbbc5645e0ddb3dddc814294a0258989d8c34e0f9e6f3567' 
  AND token = 'ppK2fQyS6XWDJ/s1JdpX/NlFYrk26Omgl+TZl1BE4mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}