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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8a6b6d703945e50bb4bce70fbd4c0412ad94132d9ff0da6a59a7af137737e2b' 
  AND token = 'bkCQ8Ge/qUEP00SEZ3C3SMmky0jrtw3E1zJer8bsIK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}