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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c4535722c998f53c60093589306324840db196234cf8e4939b0b6791a460123' 
  AND token = 'Lo0u/aM9eHyqfQ+WhCoNdb/poRCybk+QM+oLRJXvhpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}